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Company

Septerna, Inc.

SEPN · CIK 0001984086

SEC FORM 4
$9,199.08

Septerna, Inc. (SEPN)

Acquisition (code M) of 3,333 shares at $2.76 per share.

Reporting Person Long Daniel D. · Officer Title SVP, Drug Discovery · Transaction Code M

Traded Sep 1, 2026 · Disclosed Sep 3, 2026

Source: SEC Form 4 · 0001193125-26-382267 · filed 2026-09-03 · View filing →

SEC FORM 4
$126,077.72

Septerna, Inc. (SEPN)

Sale of 3,333 shares at $37.8271 per share.

Reporting Person Long Daniel D. · Officer Title SVP, Drug Discovery · Transaction Code S

Traded Sep 1, 2026 · Disclosed Sep 3, 2026

Source: SEC Form 4 · 0001193125-26-382267 · filed 2026-09-03 · View filing →

SEC FORM 4
$7,392,655.93

Septerna, Inc. (SEPN)

Sale of 147,059 shares at $50.27 per share.

Reporting Persons Third Rock Ventures V, L.P. · Third Rock Ventures GP V, LP · TRV GP V, LLC · Third Rock Ventures VI, L.P. · Third Rock Ventures GP VI, L.P. · TRV GP VI, LLC · Transaction Code S

Traded Aug 12, 2026 · Disclosed Aug 14, 2026

Source: SEC Form 4 · 0001193125-26-352692 · filed 2026-08-14 · View filing →

SEC FORM 4
$7,202.28

Septerna, Inc. (SEPN)

Sale of 141 shares at $51.08 per share.

Reporting Persons Third Rock Ventures V, L.P. · Third Rock Ventures GP V, LP · TRV GP V, LLC · Third Rock Ventures VI, L.P. · Third Rock Ventures GP VI, L.P. · TRV GP VI, LLC · Transaction Code S

Traded Aug 12, 2026 · Disclosed Aug 14, 2026

Source: SEC Form 4 · 0001193125-26-352692 · filed 2026-08-14 · View filing →

SEC FORM 4
$31,726,250.00

Septerna, Inc. (SEPN)

Sale of 746,500 shares at $42.50 per share.

Reporting Persons RA CAPITAL MANAGEMENT, L.P. · RA Capital Healthcare Fund LP · RA Capital Nexus Fund III, L.P. · Kolchinsky Peter · Shah Rajeev M. · Transaction Code S

Traded Aug 12, 2026 · Disclosed Aug 14, 2026

Source: SEC Form 4 · 0001231919-26-000938 · filed 2026-08-14 · View filing →

SEC FORM 4
$31,726,250.00

Septerna, Inc. (SEPN)

Sale of 746,500 shares at $42.50 per share.

Reporting Persons RA CAPITAL MANAGEMENT, L.P. · RA Capital Healthcare Fund LP · RA Capital Nexus Fund III, L.P. · Kolchinsky Peter · Shah Rajeev M. · Transaction Code S

Traded Aug 12, 2026 · Disclosed Aug 14, 2026

Source: SEC Form 4 · 0001231919-26-000938 · filed 2026-08-14 · View filing →

SEC FORM 4
$127,217.61

Septerna, Inc. (SEPN)

Acquisition (code M) of 18,681 shares at $6.81 per share.

Reporting Person Bhatt Elizabeth · Officer Title President and COO · Transaction Code M

Traded Aug 11, 2026 · Disclosed Aug 13, 2026

Source: SEC Form 4 · 0001193125-26-349810 · filed 2026-08-13 · View filing →

SEC FORM 4
$17,440.44

Septerna, Inc. (SEPN)

Acquisition (code M) of 6,319 shares at $2.76 per share.

Reporting Person Bhatt Elizabeth · Officer Title President and COO · Transaction Code M

Traded Aug 11, 2026 · Disclosed Aug 13, 2026

Source: SEC Form 4 · 0001193125-26-349810 · filed 2026-08-13 · View filing →

SEC FORM 4
$1,100,000.00

Septerna, Inc. (SEPN)

Sale of 25,000 shares at $44 per share.

Reporting Person Bhatt Elizabeth · Officer Title President and COO · Transaction Code S

Traded Aug 11, 2026 · Disclosed Aug 13, 2026

Source: SEC Form 4 · 0001193125-26-349810 · filed 2026-08-13 · View filing →